{"id":25577,"date":"2025-05-14T12:08:20","date_gmt":"2025-05-14T04:08:20","guid":{"rendered":"https:\/\/pi-union.com\/?p=25577"},"modified":"2025-05-15T15:36:39","modified_gmt":"2025-05-15T07:36:39","slug":"%e4%bd%8e%e9%88%89%e9%a3%b2%e9%a3%9f%e9%a1%af%e8%91%97%e9%99%8d%e4%bd%8e%e4%b8%ad%e8%80%81%e5%b9%b4%e4%ba%ba%e7%9a%84%e8%a1%80%e5%a3%93","status":"publish","type":"post","link":"https:\/\/pi-union.com\/en\/2025\/05\/14\/%e4%bd%8e%e9%88%89%e9%a3%b2%e9%a3%9f%e9%a1%af%e8%91%97%e9%99%8d%e4%bd%8e%e4%b8%ad%e8%80%81%e5%b9%b4%e4%ba%ba%e7%9a%84%e8%a1%80%e5%a3%93\/","title":{"rendered":"\u4f4e\u9209\u98f2\u98df\u986f\u8457\u964d\u4f4e\u4e2d\u8001\u5e74\u4eba\u7684\u8840\u58d3"},"content":{"rendered":"<h4 class=\"wp-block-heading\"><strong>\u98f2\u98df\u9209<\/strong><strong>(Dietary Sodium)<\/strong><strong>\u5c0d\u8840\u58d3\u7684\u5f71\u97ff\uff1a\u4e00\u9805\u4ea4\u53c9\u8a66\u9a57<\/strong><strong>(A Crossover Trial)<\/strong><\/h4>\n\n\n\n<p>Deepak K Gupta, et al.&nbsp;<\/p>\n\n\n\n<p>JAMA. 2023 Dec 19;330(23):2258-2266.&nbsp;<\/p>\n\n\n\n<p><strong>\u91cd\u8981\u6027\uff1a<\/strong><\/p>\n\n\n\n<p>\u7531\u65bc\u5c0d\u98f2\u98df\u9209(Dietary Sodium)\u651d\u53d6\u7684\u8840\u58d3(Blood Pressure, BP)\u53cd\u61c9\u4e0d\u4e00\u81f4\uff0c\u98f2\u98df\u9209\u7684\u5efa\u8b70\u5b58\u5728\u722d\u8b70\u3002\u6b64\u5916\uff0c\u6b63\u5728\u670d\u7528\u6297\u9ad8\u8840\u58d3\u85e5\u7269(antihypertensive medications)\u7684\u500b\u9ad4\u4e2d\uff0c\u98f2\u98df\u9209\u5c0d\u8840\u58d3\u7684\u5f71\u97ff\u5c1a\u672a\u5f97\u5230\u5145\u5206\u7814\u7a76\u3002<\/p>\n\n\n\n<p><strong>\u76ee\u6a19\uff1a<\/strong><\/p>\n\n\n\n<p>\u6aa2\u67e5\u500b\u9ad4\u5c0d\u98f2\u98df\u9209\u7684\u8840\u58d3\u53cd\u61c9\uff0c\u6e2c\u91cf\u5148\u98df\u7528\u9ad8\u9209\u98f2\u98df(High-sodium diet)\u6216\u4f4e\u9209\u98f2\u98df(Low-sodium diet)\u7684\u500b\u9ad4\u4e4b\u9593\u7684\u8840\u58d3\u5dee\u7570\uff0c\u4e26\u6aa2\u67e5\u9019\u4e9b\u5dee\u7570\u662f\u5426\u8207\u57fa\u7dda\u8840\u58d3(baseline BP)\u548c\u6297\u9ad8\u8840\u58d3\u85e5\u7269\u4f7f\u7528\u800c\u6709\u6240\u4e0d\u540c\u3002<\/p>\n\n\n\n<p><strong>\u8a2d\u8a08\u3001\u5730\u9ede\u548c\u53c3\u8207\u8005\uff1a<\/strong><\/p>\n\n\n\n<p>\u672c\u7814\u7a76\u65bc2021\u5e744\u6708\u81f32023\u5e742\u6708\u9593\uff0c\u5728\u5169\u500b\u7f8e\u570b\u57ce\u5e02\u4e2d\u62db\u52df\u793e\u5340\u53c3\u8207\u8005\uff0c\u9032\u884c\u524d\u77bb\u6027\u5206\u914d\u7684\u98f2\u98df\u9806\u5e8f\u8207\u4ea4\u53c9\u8a2d\u8a08\u3002\u7e3d\u5171\u6709213\u540d50\u81f375\u6b72\u7684\u500b\u9ad4\uff0c\u5305\u62ec\u6b63\u5e38\u8840\u58d3\uff0825%\uff09\u3001\u53d7\u63a7\u5236\u7684\u9ad8\u8840\u58d3\uff0820%\uff09\u3001\u672a\u53d7\u63a7\u5236\u7684\u9ad8\u8840\u58d3\uff0831%\uff09\u548c\u672a\u6cbb\u7642\u7684\u9ad8\u8840\u58d3\uff0825%\uff09\u3002\u500b\u9ad4\u5728\u5176\u5e73\u6642\u98f2\u98df\u7fd2\u6163\u7684\u57fa\u790e\u4e0a\u53c3\u8207\u8a66\u9a57\uff0c\u7136\u5f8c\u5b8c\u6210\u70ba\u671f1\u5468\u7684\u9ad8\u9209\u548c\u4f4e\u9209\u98f2\u98df\u3002<\/p>\n\n\n\n<p><strong>\u4ecb\u5165\uff1a<\/strong><\/p>\n\n\n\n<p>\u9ad8\u9209\u98f2\u98df\uff08\u6bcf\u65e5\u5728\u6b63\u5e38\u98f2\u98df\u4e2d\u6dfb\u52a0\u7d042200\u6beb\u514b\u9209\uff09\u548c\u4f4e\u9209\u98f2\u98df\uff08\u6bcf\u65e5\u7e3d\u91cf\u7d04\u70ba500\u6beb\u514b\uff09\u3002<\/p>\n\n\n\n<p><strong>\u4e3b\u8981\u7d50\u679c\u548c\u6e2c\u91cf\uff1a<\/strong><\/p>\n\n\n\n<p>\u5e73\u574724\u5c0f\u6642\u52d5\u614b\u6536\u7e2e\u58d3(systolic BP)\u548c\u8212\u5f35\u58d3(diastolic BP)\u3001\u5e73\u5747\u52d5\u8108\u58d3(arterial pressure)\u548c\u8108\u58d3(pulse pressure)\u3002<\/p>\n\n\n\n<p><strong>\u7d50\u679c\uff1a<\/strong><\/p>\n\n\n\n<p>\u5728\u5b8c\u6210\u9ad8\u9209\u548c\u4f4e\u9209\u98f2\u98df\u8a66\u9a57\u7684213\u540d\u53c3\u8207\u8005\u4e2d\uff0c\u5e74\u9f61\u4e2d\u4f4d\u6578\u70ba61\u6b72\uff0c65%\u70ba\u5973\u6027\uff0c64%\u70ba\u975e\u88d4\u7f8e\u570b\u4eba\u3002\u5728\u98df\u7528\u6b63\u5e38\u3001\u9ad8\u9209\u548c\u4f4e\u9209\u98f2\u98df\u6642\uff0c\u53c3\u8207\u8005\u7684\u6536\u7e2e\u58d3\u4e2d\u4f4d\u6578\u5206\u5225\u70ba125\u3001126\u548c119\u6beb\u7c73\u6c5e\u67f1(mm Hg)\u3002\u5728\u9ad8\u9209\u548c\u4f4e\u9209\u98f2\u98df\u4e4b\u9593\u7684\u500b\u9ad4\uff0c\u5e73\u5747\u52d5\u8108\u58d3\u8b8a\u5316\u7684\u4e2d\u4f4d\u503c\u70ba4\u6beb\u7c73\u6c5e\u67f1\uff08IQR\uff0c0-8\u6beb\u7c73\u6c5e\u67f1\uff1bP &lt;0.001\uff09\uff0c\u5728\u9ad8\u8840\u58d3\u72c0\u614b\u4e0b\u6c92\u6709\u660e\u986f\u5dee\u7570\u3002\u8207\u9ad8\u9209\u98f2\u98df\u76f8\u6bd4\uff0c<strong>\u4f4e\u9209\u98f2\u98df\u4f7f<\/strong><strong>73.4%<\/strong><strong>\u7684\u500b\u9ad4\u5e73\u5747\u52d5\u8108\u58d3\u4e0b\u964d\u3002<\/strong>\u5728\u9ad8\u9209\u548c\u4f4e\u9209\u98f2\u98df\u4e4b\u9593\uff0c\u5e73\u5747\u52d5\u8108\u58d3\u4e0b\u964d5\u6beb\u7c73\u6c5e\u67f1\u6216\u66f4\u591a\u7684\u5e38\u7528\u95be\u503c\uff0c\u5c0746%\u7684\u500b\u9ad4\u5206\u985e\u70ba\u201c\u9e7d\u654f\u611f\u201d (salt sensitive)\u65cf\u7fa4\u3002\u5728\u7b2c\u4e00\u6b21\u81b3\u98df\u4ecb\u5165\u5468\u7d50\u675f\u6642\uff0c\u9ad8\u9209\u548c\u4f4e\u9209\u98f2\u98df\u7684\u500b\u9ad4\u4e4b\u9593\u7684\u5e73\u5747\u6536\u7e2e\u58d3\u5dee\u7570\u70ba8\u6beb\u7c73\u6c5e\u67f1\uff0895% CI\uff0c4-11\u6beb\u7c73\u6c5e\u67f1\uff1bP &lt;0.001\uff09\uff0c\u5728\u5e74\u9f61\u3001\u6027\u5225\u3001\u7a2e\u65cf\u3001\u9ad8\u8840\u58d3\u3001\u57fa\u7dda\u8840\u58d3\u3001\u7cd6\u5c3f\u75c5\u548c\u9ad4\u91cd\u6307\u6578\u7b49\u5b50\u7fa4\u9ad4\u4e2d\u57fa\u672c\u76f8\u4f3c\u3002\u5728\u98df\u7528\u9ad8\u9209\u548c\u4f4e\u9209\u98f2\u98df\u6642\uff0c9.9%\u548c8.0%\u7684\u500b\u9ad4\u5831\u544a\u4e86\u8f15\u5fae\u7684\u4e0d\u826f\u4e8b\u4ef6(adverse events)\uff0c\u5831\u544a\u7684\u4e0d\u826f\u4e8b\u4ef6\u8207\u98f2\u98df\u7121\u95dc\u3002<\/p>\n\n\n\n<p><strong>\u7d50\u8ad6\u548c\u76f8\u95dc\u6027\uff1a<\/strong><\/p>\n\n\n\n<p><strong>\u964d\u4f4e\u98f2\u98df\u9209\u542b\u91cf\u986f\u8457\u964d\u4f4e\u4e86\u5927\u591a\u6578\u4e2d\u8001\u5e74\u4eba\u7684\u8840\u58d3\u3002<\/strong>\u5f9e\u9ad8\u9209\u98f2\u98df\u5230\u4f4e\u9209\u98f2\u98df\u7684\u8840\u58d3\u4e0b\u964d\u7368\u7acb\u65bc\u9ad8\u8840\u58d3\u72c0\u614b\u548c\u6297\u9ad8\u8840\u58d3\u85e5\u7269\u7684\u4f7f\u7528\uff0c\u8a72\u7d50\u679c\u5728\u5b50\u7fa4\u9ad4\u4e2d\u4fdd\u6301\u4e00\u81f4\uff0c\u4e26\u4e14\u6c92\u6709\u5c0e\u81f4\u904e\u591a\u7684\u4e0d\u826f\u4e8b\u4ef6\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">\u8a55\u8ad6\uff1a\u98f2\u98df\u9209\u651d\u53d6\u8207\u8840\u58d3\u63a7\u5236 \u2014 \u4ea4\u53c9\u8a66\u9a57\u63d0\u4f9b\u6709\u529b\u8b49\u64da\u652f\u6301\u6e1b\u9209\u7b56\u7565<\/h4>\n\n\n\n<p>Gupta\u7b49\u4eba\u65bc2023\u5e74\u767c\u8868\u7684\u9019\u9805\u4ea4\u53c9\u8a66\u9a57\uff0c\u7cfb\u7d71\u6027\u5730\u8a55\u4f30\u4e86<strong>\u98f2\u98df\u9209\u5c0d\u4e2d\u8001\u5e74\u6210\u4eba\u8840\u58d3\u7684\u5f71\u97ff<\/strong>\uff0c\u5176\u7d50\u679c\u5c0d\u516c\u5171\u885b\u751f\u548c\u81e8\u5e8a\u7ba1\u7406\u90fd\u5177\u6709\u91cd\u8981\u555f\u793a\u3002<\/p>\n\n\n\n<p>\u672c\u7814\u7a76\u7684\u8a2d\u8a08\u56b4\u8b39\uff0c\u63a1\u7528\u524d\u77bb\u6027\u98f2\u98df\u9806\u5e8f\u4ea4\u53c9\u65b9\u6cd5\uff0c\u8b93\u540c\u4e00\u53d7\u8a66\u8005\u5206\u5225\u63a5\u53d7\u9ad8\u9209\u8207\u4f4e\u9209\u98f2\u98df\u4ecb\u5165\uff0c\u6975\u5927\u5730\u964d\u4f4e\u4e86\u500b\u9ad4\u5dee\u7570\u7684\u5e72\u64fe\uff0c\u63d0\u9ad8\u7d50\u679c\u7684\u53ef\u9760\u6027\u3002\u53c3\u8207\u8005\u6db5\u84cb\u6b63\u5e38\u8840\u58d3\u8005\u3001\u53d7\u63a7\u8207\u672a\u53d7\u63a7\u9ad8\u8840\u58d3\u60a3\u8005\uff0c\u4ee5\u53ca\u672a\u6cbb\u7642\u9ad8\u8840\u58d3\u8005\uff0c\u5448\u73fe\u591a\u6a23\u5316\u7684\u81e8\u5e8a\u80cc\u666f\uff0c\u589e\u52a0\u4e86\u7d50\u679c\u7684\u5916\u90e8\u9069\u7528\u6027\u3002<\/p>\n\n\n\n<p>\u7814\u7a76\u767c\u73fe\uff0c\u4f4e\u9209\u98f2\u98df\u76f8\u8f03\u9ad8\u9209\u98f2\u98df\u53ef\u4f7f73.4%\u53c3\u8207\u8005\u7684\u5e73\u5747\u52d5\u8108\u58d3\u986f\u8457\u4e0b\u964d\uff0c\u8fd1\u534a\u6578\uff0846%\uff09\u5c6c\u65bc\u300c\u9e7d\u654f\u611f\u300d\u65cf\u7fa4\uff0c\u8840\u58d3\u4e0b\u964d\u5e45\u5ea6\u90545\u6beb\u7c73\u6c5e\u67f1\u4ee5\u4e0a\uff0c\u9019\u4e00\u9ede\u5c24\u5176\u503c\u5f97\u81e8\u5e8a\u91cd\u8996\u3002\u6b64\u5916\uff0c\u8840\u58d3\u964d\u5e45\u5728\u4e0d\u540c\u5e74\u9f61\u3001\u6027\u5225\u3001\u7a2e\u65cf\u53ca\u9ad8\u8840\u58d3\u72c0\u614b\u7684\u5b50\u7fa4\u9ad4\u9593\u8868\u73fe\u4e00\u81f4\uff0c\u986f\u793a\u6e1b\u9209\u7b56\u7565\u666e\u904d\u9069\u7528\uff0c\u4e14\u4e0d\u53d7\u6297\u9ad8\u8840\u58d3\u85e5\u7269\u4f7f\u7528\u8207\u5426\u5f71\u97ff\u3002<\/p>\n\n\n\n<p>\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u7814\u7a76\u671f\u9593\u672a\u898b\u660e\u986f\u8207\u98f2\u98df\u76f8\u95dc\u7684\u4e0d\u826f\u4e8b\u4ef6\uff0c\u8b49\u5be6\u77ed\u671f\u5167\u7684\u4f4e\u9209\u98f2\u98df\u662f\u5b89\u5168\u7684\uff0c\u9019\u70ba\u63a8\u52d5\u6e1b\u9209\u516c\u5171\u885b\u751f\u653f\u7b56\u63d0\u4f9b\u4e86\u6709\u529b\u652f\u6301\u3002<\/p>\n\n\n\n<p>\u6b64\u7814\u7a76\u88dc\u5f37\u4e86\u6e1b\u5c11\u98f2\u98df\u9209\u651d\u5165\u4ee5\u63a7\u5236\u8840\u58d3\u3001\u9810\u9632\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u79d1\u5b78\u57fa\u790e\uff0c\u5c24\u5176\u662f\u5728\u5168\u7403\u9ad8\u8840\u58d3\u76db\u884c\u7387\u6500\u5347\u7684\u80cc\u666f\u4e0b\u3002\u9452\u65bc\u4e0d\u5c11\u4eba\u5c0d\u6e1b\u9209\u6548\u76ca\u4ecd\u5b58\u5728\u7591\u616e\uff0c\u8a72\u4ea4\u53c9\u8a66\u9a57\u4ee5\u56b4\u8b39\u65b9\u6cd5\u548c\u591a\u5143\u6a23\u672c\u5c55\u793a\u4e86\u6e05\u6670\u3001\u53ef\u6e2c\u91cf\u7684\u8840\u58d3\u6539\u5584\uff0c\u5c0d\u81e8\u5e8a\u91ab\u5e2b\u8207\u516c\u5171\u885b\u751f\u6c7a\u7b56\u8005\u5177\u9ad8\u5ea6\u53c3\u8003\u50f9\u503c\u3002<\/p>\n\n\n\n<p>\u7d9c\u4e0a\uff0c<strong>\u964d\u4f4e\u98f2\u98df\u9209\u651d\u5165\u61c9\u6210\u70ba\u4e2d\u8001\u5e74\u4eba\u53ca\u9ad8\u8840\u58d3\u60a3\u8005\u7684\u5065\u5eb7\u5efa\u8b70\u5e38\u898f\u4e4b\u4e00<\/strong>\uff0c\u4e26\u7d50\u5408\u5176\u4ed6\u751f\u6d3b\u65b9\u5f0f\u6539\u8b8a\uff0c\u624d\u80fd\u66f4\u6709\u6548\u6e1b\u5c11\u5fc3\u8840\u7ba1\u75be\u75c5\u8ca0\u64d4\u3002\u672a\u4f86\u53ef\u8003\u616e\u9577\u671f\u96a8\u8a2a\u7814\u7a76\uff0c\u4ee5\u8a55\u4f30\u6301\u7e8c\u6e1b\u9209\u5c0d\u5fc3\u8840\u7ba1\u4e8b\u4ef6\u7684\u5f71\u97ff\u53ca\u6700\u4f73\u6e1b\u9209\u76ee\u6a19\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>\u7de8\u8b6f\u8207\u8a55\u8ad6: <a href=\"https:\/\/pi-union.com\/en\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u767e\u806f\u91ab\u5b78\u7de8\u8b6f<\/a><\/p>\n\n\n\n<p>Translator and Reviewer: \u00a0<a href=\"https:\/\/pi-union.com\/en\/\" target=\"_blank\" rel=\"noreferrer noopener\">PI-Union Medical Science<\/a><\/p>\n\n\n\n<p>Source:<\/p>\n\n\n\n<p><a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2811931?guestAccessKey=8bac1209-9142-4724-b96d-a63882cd0a5d&amp;utm_source=silverchair&amp;utm_medium=email&amp;utm_campaign=article_alert-jama&amp;utm_term=mostread&amp;utm_content=olf-widget_12282023&amp;adv=000005025454\" target=\"_blank\" rel=\"noreferrer noopener\">Effect of Dietary Sodium on Blood Pressure<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>\u70ba\u5584\u6700\u6a02\uff0c\u8acb\u652f\u6301\u4ee5\u4e0b\u516c\u76ca\u793e\u798f\u6a5f\u69cb:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"http:\/\/www.ccft.org.tw\/OnePage.aspx?tid=157&amp;id=424\" target=\"_blank\" rel=\"noreferrer noopener\">\u8ca1\u5718\u6cd5\u4eba\u4e2d\u83ef\u6c11\u570b\u5fc3\u81df\u75c5\u5152\u7ae5\u57fa\u91d1\u6703<\/a><\/li>\n\n\n\n<li><a href=\"http:\/\/www.tsoc-thf.org.tw\/index.asp\" target=\"_blank\" rel=\"noreferrer noopener\">\u8ca1\u5718\u6cd5\u4eba\u4e2d\u83ef\u6c11\u570b\u5fc3\u81df\u57fa\u91d1\u6703<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.ths.org.tw\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u53f0\u7063\u9ad8\u8840\u58d3\u5b78\u6703<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u98f2\u98df\u9209(Dietary Sodium)\u5c0d\u8840\u58d3\u7684\u5f71\u97ff\uff1a\u4e00\u9805\u4ea4\u53c9\u8a66\u9a57(A Crossover Trial) Dee [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":25578,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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