{"id":25483,"date":"2025-05-10T22:43:18","date_gmt":"2025-05-10T14:43:18","guid":{"rendered":"https:\/\/pi-union.com\/?p=25483"},"modified":"2025-05-15T18:24:35","modified_gmt":"2025-05-15T10:24:35","slug":"%e7%b6%93%e5%b0%8e%e7%ae%a1%e7%93%a3%e8%86%9c%e4%bf%ae%e5%be%a9%e8%a1%93%e5%9c%a8%e4%b8%ad%e5%ba%a6%e8%87%b3%e9%87%8d%e5%ba%a6%e4%ba%8c%e5%b0%96%e7%93%a3%e9%96%89%e9%8e%96%e4%b8%8d%e5%85%a8%e5%bf%83","status":"publish","type":"post","link":"https:\/\/pi-union.com\/zh\/2025\/05\/10\/%e7%b6%93%e5%b0%8e%e7%ae%a1%e7%93%a3%e8%86%9c%e4%bf%ae%e5%be%a9%e8%a1%93%e5%9c%a8%e4%b8%ad%e5%ba%a6%e8%87%b3%e9%87%8d%e5%ba%a6%e4%ba%8c%e5%b0%96%e7%93%a3%e9%96%89%e9%8e%96%e4%b8%8d%e5%85%a8%e5%bf%83\/","title":{"rendered":"\u7ecf\u5bfc\u7ba1\u74e3\u819c\u4fee\u590d\u672f\u5728\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u4e8c\u5c16\u74e3\u95ed\u9501\u4e0d\u5168\u5fc3\u810f\u8870\u7aed\u4e2d\u7684\u5e94\u7528"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\">\u7d93\u5c0e\u7ba1\u74e3\u819c\u4fee\u5fa9\u8853\u5728\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u4e8c\u5c16\u74e3\u9589\u9396\u4e0d\u5168\u5fc3\u81df\u8870\u7aed\u4e2d\u7684\u61c9\u7528<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Stefan D.Anker, et al.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">N Engl J Med. 2024 Nov 14;391(19):1799-1809.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u6458\u8981<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u80cc\u666f<\/strong><br>\u7d93\u5c0e\u7ba1\u4e8c\u5c16\u74e3\u4fee\u5fa9\u8853(Transcatheter Valve Repair)\u662f\u5426\u80fd\u6539\u5584\u4f34\u6709\u5fc3\u81df\u8870\u7aed(Heart Failure)\u53ca\u529f\u80fd\u6027\u4e8c\u5c16\u74e3\u9589\u9396\u4e0d\u5168(Mitral Regurgitation, MR)\u60a3\u8005\u7684\u81e8\u5e8a\u7d50\u5c40\u4ecd\u4e0d\u78ba\u5b9a\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u65b9\u6cd5<\/strong><br>\u6211\u5011\u57289\u500b\u570b\u5bb630\u500b\u5730\u9ede\u9032\u884c\u4e86\u4e00\u9805\u96a8\u6a5f\u5c0d\u7167\u8a66\u9a57\uff0c\u7d0d\u5165\u60a3\u6709\u5fc3\u81df\u8870\u7aed\u53ca\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u529f\u80fd\u6027\u4e8c\u5c16\u74e3\u9589\u9396\u4e0d\u5168\u7684\u60a3\u8005\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u60a3\u8005\u6309\u71671:1\u7684\u6bd4\u4f8b\u96a8\u6a5f\u5206\u914d\u81f3\u7d93\u5c0e\u7ba1\u4e8c\u5c16\u74e3\u4fee\u5fa9\u8853\u4e26\u63a5\u53d7\u6307\u5c0e\u6027\u5efa\u8b70\u7684\u85e5\u7269\u6cbb\u7642\uff08\u5668\u68b0\u7d44\uff09\u6216\u50c5\u63a5\u53d7\u85e5\u7269\u6cbb\u7642\uff08\u5c0d\u7167\u7d44\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7814\u7a76\u7684\u4e09\u500b\u4e3b\u8981\u7d42\u9ede(end points)\u5305\u62ec\uff1a<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\u572824\u500b\u6708\u5167\u9996\u6b21\u6216\u5fa9\u767c\u6027\u5fc3\u81df\u8870\u7aed\u4f4f\u9662\u6216\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u7684\u8907\u5408\u4e8b\u4ef6\u7387\uff1b<\/li>\n\n\n\n<li>24\u500b\u6708\u5167\u9996\u6b21\u6216\u5fa9\u767c\u6027\u5fc3\u81df\u8870\u7aed\u4f4f\u9662\u7387\uff1b<\/li>\n\n\n\n<li>\u4ee5\u53ca\u5f9e\u57fa\u7dda(baseline)\u523012\u500b\u6708\u5728\u582a\u85a9\u65af\u57ce\u5fc3\u808c\u75c7\u554f\u5377\u7e3d\u5206 (the Kansas City Cardiomyopathy Questionnaire-Overall Summary, KCCQ-OS\uff09\u4e2d\u7684\u5f97\u5206\u8b8a\u5316\uff08\u5f97\u5206\u7bc4\u570d\u70ba0\u5230100\u5206\uff0c\u5206\u6578\u8d8a\u9ad8\u8868\u793a\u5065\u5eb7\u72c0\u614b\u8d8a\u597d\uff09\u3002<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7d50\u679c<\/strong><br>\u5171\u6709505\u540d\u60a3\u8005\u88ab\u96a8\u6a5f\u5206\u914d\uff0c\u5176\u4e2d250\u540d\u5206\u914d\u81f3\u5668\u68b0\u7d44\uff0c255\u540d\u5206\u914d\u81f3\u5c0d\u7167\u7d44\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u572824\u500b\u6708\u5167\uff0c\u5668\u68b0\u7d44\u7684\u9996\u6b21\u6216\u5fa9\u767c\u6027\u5fc3\u81df\u8870\u7aed\u4f4f\u9662\u6216\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u4e8b\u4ef6\u767c\u751f\u7387\u70ba\u6bcf100\u4eba\u5e7437.0\u6b21\uff0c\u800c\u5c0d\u7167\u7d44\u70ba\u6bcf100\u4eba\u5e7458.9\u6b21\uff08rate ratio\uff0c0.64\uff1b95%\u4fe1\u8cf4\u5340\u9593[CI]\uff0c0.48\u81f30.85\uff1bP=0.002\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9996\u6b21\u6216\u5fa9\u767c\u6027\u5fc3\u81df\u8870\u7aed\u4f4f\u9662\u7387\u5728\u5668\u68b0\u7d44\u70ba\u6bcf100\u4eba\u5e7426.9\u6b21\uff0c\u800c\u5c0d\u7167\u7d44\u70ba\u6bcf100\u4eba\u5e7446.6\u6b21\uff08rate ratio\uff0c0.59\uff1b95% CI\uff0c0.42\u81f30.82\uff1bP=0.002\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">KCCQ-OS\u5f97\u5206\u5728\u5668\u68b0\u7d44\u5e73\u5747\u589e\u52a021.6\u00b126.9\u5206\uff0c\u800c\u5c0d\u7167\u7d44\u70ba8.0\u00b124.5\u5206\uff08\u5e73\u5747\u5dee\u7570\uff0c10.9\u5206\uff1b95% CI\uff0c6.8\u81f315.0\uff1bP&lt;0.001\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5668\u68b0\u76f8\u95dc\u7684\u5b89\u5168\u4e8b\u4ef6\u767c\u751f\u65bc4\u540d\u60a3\u8005\uff081.6%\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7d50\u8ad6<\/strong><br>\u5728\u63a5\u53d7\u85e5\u7269\u6cbb\u7642\u7684\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u529f\u80fd\u6027\u4e8c\u5c16\u74e3\u9589\u9396\u4e0d\u5168\u5fc3\u81df\u8870\u7aed\u60a3\u8005\u4e2d\uff0c\u52a0\u5165\u7d93\u5c0e\u7ba1\u4e8c\u5c16\u74e3\u4fee\u5fa9\u8853\u53ef\u572824\u500b\u6708\u5167\u986f\u8457\u964d\u4f4e\u9996\u6b21\u6216\u5fa9\u767c\u6027\u5fc3\u81df\u8870\u7aed\u4f4f\u9662\u6216\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u7684\u767c\u751f\u7387\uff0c\u4ee5\u53ca\u9996\u6b21\u6216\u5fa9\u767c\u6027\u5fc3\u81df\u8870\u7aed\u4f4f\u9662\u7387\uff1b\u572812\u500b\u6708\u5167\uff0c\u60a3\u8005\u7684\u5065\u5eb7\u72c0\u614b\u4ea6\u512a\u65bc\u50c5\u63a5\u53d7\u85e5\u7269\u6cbb\u7642\u7684\u60a3\u8005\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">\u8a55\u8ad6:<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">\u9019\u9805\u4f86\u81ea\u300a\u65b0\u82f1\u683c\u862d\u91ab\u5b78\u96dc\u8a8c\u300b\u7684\u591a\u570b\u3001\u591a\u4e2d\u5fc3\u96a8\u6a5f\u5c0d\u7167\u8a66\u9a57\uff0c\u91dd\u5c0d\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u529f\u80fd\u6027\u4e8c\u5c16\u74e3\u9589\u9396\u4e0d\u5168\u5408\u4f75\u5fc3\u81df\u8870\u7aed\u60a3\u8005\uff0c\u8a55\u4f30\u4e86\u7d93\u5c0e\u7ba1\u4e8c\u5c16\u74e3\u4fee\u5fa9\u8853\uff08Transcatheter Valve Repair, TVR\uff09\u52a0\u85e5\u7269\u6cbb\u7642\u8207\u55ae\u7d14\u85e5\u7269\u6cbb\u7642\u7684\u7642\u6548\u53ca\u5b89\u5168\u6027\uff0c\u63d0\u4f9b\u4e86\u6975\u5177\u81e8\u5e8a\u50f9\u503c\u7684\u8b49\u64da\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9996\u5148\uff0c\u7814\u7a76\u5728\u60a3\u8005\u5206\u7d44\u53ca\u8ffd\u8e64\u671f\u9593\u8a2d\u8a08\u56b4\u8b39\uff0c\u96a8\u6a5f\u5206\u914d\u6709\u52a9\u65bc\u6e1b\u5c11\u504f\u5dee\uff0c\u4e14\u7d42\u9ede\u8a2d\u5b9a\u517c\u9867\u81e8\u5e8a\u91cd\u8981\u7684\u4e8b\u4ef6\uff08\u5fc3\u81df\u8870\u7aed\u4f4f\u9662\u548c\u5fc3\u8840\u7ba1\u6b7b\u4ea1\uff09\u53ca\u60a3\u8005\u751f\u6d3b\u54c1\u8cea\uff08KCCQ-OS\u554f\u5377\uff09\uff0c\u5448\u73fe\u5168\u9762\u7684\u7642\u6548\u8a55\u4f30\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7d50\u679c\u986f\u793a\uff0c\u5668\u68b0\u7d44\u60a3\u8005\u572824\u500b\u6708\u5167\u9996\u6b21\u6216\u5fa9\u767c\u6027\u5fc3\u81df\u8870\u7aed\u4f4f\u9662\u53ca\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u7684\u8907\u5408\u4e8b\u4ef6\u7387\u986f\u8457\u964d\u4f4e\uff0c\u4f4f\u9662\u7387\u4ea6\u6709\u660e\u986f\u6539\u5584\uff0c\u4e14\u751f\u6d3b\u54c1\u8cea\u6307\u6a19\u63d0\u5347\u660e\u986f\uff0c\u53cd\u6620\u7d93\u5c0e\u7ba1\u4fee\u5fa9\u8853\u4e0d\u50c5\u80fd\u5ef6\u9577\u60a3\u8005\u5b58\u6d3b\uff0c\u66f4\u63d0\u5347\u751f\u6d3b\u529f\u80fd\u8207\u5065\u5eb7\u611f\u53d7\uff0c\u5c0d\u60a3\u8005\u548c\u91ab\u7642\u7cfb\u7d71\u7686\u5177\u6b63\u9762\u610f\u7fa9\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6b64\u5916\uff0c1.6%\u7684\u5668\u68b0\u76f8\u95dc\u56b4\u91cd\u4e0d\u826f\u4e8b\u4ef6\u767c\u751f\u7387\u76f8\u5c0d\u4f4e\uff0c\u8b49\u660e\u8a72\u4ecb\u5165\u5177\u6709\u826f\u597d\u7684\u5b89\u5168\u6027\uff0c\u9019\u5c0d\u65bc\u9ad8\u98a8\u96aa\u7684\u5fc3\u81df\u8870\u7aed\u60a3\u8005\u5c24\u5176\u91cd\u8981\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7136\u800c\uff0c\u672c\u7814\u7a76\u4ecd\u5b58\u5728\u5e7e\u9ede\u503c\u5f97\u95dc\u6ce8\uff1a\u9996\u5148\uff0c\u96a8\u8a2a\u671f\u9593\u70ba24\u500b\u6708\uff0c\u9700\u9577\u671f\u8cc7\u6599\u4ee5\u8a55\u4f30\u6301\u7e8c\u7642\u6548\u53ca\u665a\u671f\u4f75\u767c\u75c7\uff1b\u5176\u6b21\uff0c\u60a3\u8005\u9078\u64c7\u548c\u4e2d\u5fc3\u7d93\u9a57\u53ef\u80fd\u5f71\u97ff\u7d50\u679c\u7684\u5ee3\u6cdb\u9069\u7528\u6027\uff1b\u6700\u5f8c\uff0c\u7d93\u5c0e\u7ba1\u4fee\u5fa9\u8853\u7684\u6210\u672c\u8207\u8cc7\u6e90\u9700\u6c42\u5728\u4e0d\u540c\u91ab\u7642\u74b0\u5883\u4e0b\u7684\u5be6\u65bd\u6311\u6230\u4e5f\u9700\u8003\u616e\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7e3d\u7d50\u800c\u8a00\uff0c\u6b64\u7814\u7a76\u70ba\u529f\u80fd\u6027\u4e8c\u5c16\u74e3\u9589\u9396\u4e0d\u5168\u5408\u4f75\u5fc3\u8870\u60a3\u8005\u7684\u6cbb\u7642\u7b56\u7565\u63d0\u4f9b\u4e86\u6709\u529b\u652f\u6301\uff0c\u7d93\u5c0e\u7ba1\u4e8c\u5c16\u74e3\u4fee\u5fa9\u8853\u4f5c\u70ba\u85e5\u7269\u6cbb\u7642\u7684\u88dc\u5145\uff0c\u80fd\u6709\u6548\u964d\u4f4e\u56b4\u91cd\u81e8\u5e8a\u4e8b\u4ef6\uff0c\u4e26\u63d0\u5347\u60a3\u8005\u751f\u6d3b\u54c1\u8cea\u3002\u672a\u4f86\u53ef\u9032\u4e00\u6b65\u63a2\u8a0e\u4e0d\u540c\u60a3\u8005\u4e9e\u7fa4\u7684\u7642\u6548\u5dee\u7570\u53ca\u6700\u4f73\u6642\u6a5f\uff0c\u6709\u52a9\u65bc\u81e8\u5e8a\u500b\u5225\u5316\u6cbb\u7642\u6c7a\u7b56\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\">Source:&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2314328?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200pubmed\" target=\"_blank\" rel=\"noreferrer noopener\">Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Translator and Reviewer: <a href=\"https:\/\/course.pi-union.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">PI-Union Medical Science Ltd.<\/a><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7de8\u8b6f\u8207\u8a55\u8ad6: <a href=\"https:\/\/pi-union.com\/\">\u767e\u806f\u91ab\u5b78\u7de8\u8b6f<\/a><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>E-mail: <a href=\"mailto:piunion@pi-union.com\">piunion@pi-union.com<\/a><\/li>\n\n\n\n<li>Online Courses: <a href=\"https:\/\/course.pi-union.com\/\">course.pi-union.com<\/a><\/li>\n\n\n\n<li>Official Website: <a href=\"https:\/\/pi-union.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pi-union.com\/<\/a><\/li>\n\n\n\n<li>Facebook: <a href=\"https:\/\/www.facebook.com\/piunion2020\/\" target=\"_blank\" rel=\"noreferrer noopener\">www.facebook.com\/piunion2020<\/a><\/li>\n\n\n\n<li>Youtube: <a href=\"https:\/\/www.youtube.com\/@pi-union\">www.youtube.com\/@pi-union<\/a><\/li>\n\n\n\n<li>Instagram: <a href=\"https:\/\/www.instagram.com\/piunion2020\/\">www.instagram.com\/piunion2020<\/a><\/li>\n\n\n\n<li>LINE: @654eukag<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u7d93\u5c0e\u7ba1\u74e3\u819c\u4fee\u5fa9\u8853\u5728\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u4e8c\u5c16\u74e3\u9589\u9396\u4e0d\u5168\u5fc3\u81df\u8870\u7aed\u4e2d\u7684\u61c9\u7528 Stefan D.Anker, et al.&#038;nb 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