{"id":25546,"date":"2025-05-11T19:18:18","date_gmt":"2025-05-11T11:18:18","guid":{"rendered":"https:\/\/pi-union.com\/?p=25546"},"modified":"2025-05-15T17:22:38","modified_gmt":"2025-05-15T09:22:38","slug":"%e9%9d%88%e6%80%a7%e5%8f%af%e8%aa%bf%e7%af%80%e7%99%8c%e7%97%87%e7%85%a7%e9%a1%a7%e8%80%85%e7%9a%84%e8%b2%a0%e8%8d%b7%e8%88%87%e6%86%82%e9%ac%b1","status":"publish","type":"post","link":"https:\/\/pi-union.com\/zh\/2025\/05\/11\/%e9%9d%88%e6%80%a7%e5%8f%af%e8%aa%bf%e7%af%80%e7%99%8c%e7%97%87%e7%85%a7%e9%a1%a7%e8%80%85%e7%9a%84%e8%b2%a0%e8%8d%b7%e8%88%87%e6%86%82%e9%ac%b1\/","title":{"rendered":"\u7075\u6027\u53ef\u8c03\u8282\u764c\u75c7\u7167\u987e\u8005\u7684\u8d1f\u8377\u4e0e\u5fe7\u90c1"},"content":{"rendered":"<h3 class=\"wp-block-heading\"><strong>\u9748\u6027\u8abf\u7bc0\u764c\u75c7\u7167\u9867\u8005\u8ca0\u8377\u8207\u6182\u9b31\u75c7\u72c0\u4e4b\u9593\u7684\u95dc\u4fc2<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">La IS, Johantgen M, Storr CL, Zhu S, Cagle JG, Ross A.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Palliative &amp; Supportive Care.<\/em>2024 Jun;22(3):470-481.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7814\u7a76\u76ee\u7684\uff1a<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u764c\u75c7\u5df2\u6210\u70ba\u4e00\u7a2e\u9700\u8981\u5927\u91cf\u975e\u6b63\u5f0f\u8b77\u7406\u7684\u6162\u6027\u75be\u75c5\uff0c\u9019\u5c0d\u5bb6\u5ead\u7167\u9867\u8005\u4f86\u8aaa\u901a\u5e38\u662f\u4e00\u7a2e\u76f8\u7576\u6c89\u91cd\u7684\u8ca0\u64d4\u3002\u7136\u800c\uff0c\u9748\u6027\u5c0d\u7167\u9867\u8005\u8ca0\u64d4\u548c\u5fc3\u7406\u5065\u5eb7\u7d50\u679c\u7684\u5f71\u97ff\u5c1a\u672a\u5f97\u5230\u5145\u5206\u7814\u7a76\u3002\u672c\u7814\u7a76\u65e8\u5728\u63a2\u8a0e\u5728\u764c\u75c7\u6cbb\u7642\u904e\u7a0b\u4e2d\uff0c\u7167\u9867\u8005\u8ca0\u64d4\u3001\u9748\u6027\u548c\u6182\u9b31\u75c7\u72c0\u5982\u4f55\u8b8a\u5316\uff0c\u4e26\u8abf\u67e5\u9748\u6027\u5728\u7167\u9867\u8005\u8ca0\u64d4\u8207\u6182\u9b31\u75c7\u72c0\u4e4b\u9593\u95dc\u4fc2\u4e2d\u7684\u8abf\u7bc0\u4f5c\u7528\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7814\u7a76\u65b9\u6cd5\uff1a<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9019\u9805\u4e8c\u6b21\u5206\u6790\u4f7f\u7528\u9577\u671f\u8ffd\u8e64\u7814\u7a76\uff0c\u9032\u884c\u4e09\u6b21\u6578\u64da\u6536\u96c6\uff08baseline\u30013\u500b\u6708\u548c6\u500b\u6708\uff09\u3002\u5bb6\u5ead\u7167\u9867\u8005\u5b8c\u6210\u4e86\u300a\u7167\u9867\u8005\u53cd\u61c9\u8a55\u4f30\u300b\u3001\u300a\u9748\u6027\u89c0\u9ede\u91cf\u8868\u300b\u548cPROMIS\u00ae\u6182\u9b31\u6e2c\u91cf\u5de5\u5177\u3002\u4f7f\u7528\u6df7\u5408\u7dda\u6027\u6a21\u578b(Linear mixed model)\u9032\u884c\u5206\u6790\uff0c\u4e26\u63a7\u5236\u76f8\u95dc\u7684\u5171\u8b8a\u6578\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7814\u7a76\u7d50\u679c\uff1a<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9748\u6027\u3001\u7e3d\u9ad4\u7167\u9867\u8005\u8ca0\u64d4\u548c\u6182\u9b31\u75c7\u72c0\u57286\u500b\u6708\u5167\u4fdd\u6301\u7a69\u5b9a\u3002\u5728\u4e09\u500b\u6642\u9593\u9ede\u4e2d\uff0c<strong>\u8d85\u904e30%\u7684\u7167\u9867\u8005\u6709\u8f15\u5ea6\u81f3\u91cd\u5ea6\u7684\u6182\u9b31\u75c7\u72c0<\/strong>\u3002\u6709\u8b49\u64da\u8868\u660e\uff0c\u6574\u9ad4\u8ca0\u8377\u5c0d\u6182\u9b31\u75c7\u72c0\u6709\u5f71\u97ff\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c<strong>\u7167\u9867\u8005\u7684\u9748\u6027\u5c0d\u6182\u9b31\u75c7\u72c0\u548c\u7167\u9867\u8005\u8ca0\u8377\u4e4b\u9593\u7684\u95dc\u4fc2\u6709\u4fdd\u8b77\u4f5c\u7528<\/strong>\uff08b = -1.35, p = .015\uff09\u3002\u9748\u6027\u8d8a\u4f4e\uff0c\u6182\u9b31\u75c7\u72c0\u8207\u8ca0\u64d4\u4e4b\u9593\u7684\u95dc\u4fc2\u8d8a\u5f37\uff0c\u7279\u5225\u662f\u5728\u884c\u7a0b\u8ca0\u64d4\u3001\u7d93\u6fdf\u8ca0\u64d4\u548c\u7f3a\u4e4f\u5bb6\u5ead\u652f\u6301\u7684\u5b50\u91cf\u8868\u4e0a\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7814\u7a76\u7d50\u679c\u548c\u610f\u7fa9\uff1a<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9748\u6027\u662f\u61c9\u5c0d\u7167\u9867\u6311\u6230\u7684\u91cd\u8981\u8cc7\u6e90\u3002\u672c\u7814\u7a76\u8868\u660e\uff0c\u5c0d\u764c\u75c7\u7167\u9867\u8005\u9032\u884c\u5168\u9762\u7684\u8abf\u67e5\u548c\u9748\u6027\u8b77\u7406\uff0c\u53ef\u80fd\u6539\u5584\u4ed6\u5011\u7684\u764c\u75c7\u7167\u9867\u7d93\u9a57\uff0c\u4e26\u53ef\u80fd\u5f71\u97ff\u53d7\u7167\u9867\u8005\u7684\u5065\u5eb7\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">\u8a55\u8ad6\uff1a\u9748\u6027\u4f5c\u70ba\u764c\u75c7\u7167\u9867\u8005\u5fc3\u7406\u58d3\u529b\u7684\u8abf\u7bc0\u8cc7\u6e90<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">La \u7b49\u4eba\u65bc 2024 \u5e74\u767c\u8868\u7684\u9019\u7bc7\u7814\u7a76\uff0c\u7cbe\u78ba\u5730\u6307\u51fa\u5728\u9577\u671f\u764c\u75c7\u7167\u9867\u60c5\u5883\u4e2d\uff0c\u300c\u9748\u6027\u300d\u4e0d\u50c5\u662f\u500b\u4eba\u4fe1\u5ff5\u8207\u6170\u85c9\u7684\u4f86\u6e90\uff0c\u66f4\u53ef\u80fd\u662f\u6e1b\u8f15\u5fc3\u7406\u8ca0\u64d4\u8207\u6182\u9b31\u7684\u91cd\u8981\u5fc3\u7406\u4fdd\u8b77\u56e0\u5b50\u3002\u8a72\u7814\u7a76\u5c0d\u65bc\u6574\u5408\u9748\u6027\u7167\u8b77\u9032\u5165\u764c\u75c7\u7167\u9867\u6a21\u5f0f\uff0c\u5177\u6709\u9ad8\u5ea6\u555f\u767c\u6027\u8207\u5be6\u52d9\u610f\u7fa9\u3002<\/p>\n\n\n\n<h5 class=\"wp-block-heading\">1. \u7167\u9867\u8005\u8ca0\u8377\uff1a\u4e0d\u53ef\u5ffd\u8996\u7684\u96b1\u6027\u6210\u672c<\/h5>\n\n\n\n<p class=\"wp-block-paragraph\">\u764c\u75c7\u4f5c\u70ba\u6162\u6027\u75be\u75c5\uff0c\u5176\u6cbb\u7642\u8207\u6062\u5fa9\u9031\u671f\u9577\uff0c\u5c0e\u81f4\u5bb6\u5ead\u7167\u9867\u8005\u9762\u81e8\u6301\u7e8c\u6027\u7684\u300c\u7167\u9867\u8005\u8ca0\u8377\u300d\uff0c\u9019\u4e0d\u50c5\u5305\u62ec\u5be6\u969b\u7684\u884c\u7a0b\u8207\u7d93\u6fdf\u58d3\u529b\uff0c\u4e5f\u6d89\u53ca\u5b64\u7acb\u3001\u5bb6\u5ead\u652f\u6301\u4e0d\u8db3\u3001\u8207\u5fc3\u7406\u67af\u7aed\u7b49\u8907\u5408\u58d3\u529b\u3002\u672c\u7814\u7a76\u986f\u793a\uff0c\u5728 6 \u500b\u6708\u5167\uff0c\u9ad8\u9054\u4e09\u5206\u4e4b\u4e00\u7684\u7167\u9867\u8005\u6301\u7e8c\u51fa\u73fe\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u7684\u6182\u9b31\u75c7\u72c0\uff0c\u53cd\u6620\u51fa\u9019\u4e00\u7fa4\u9ad4\u7684\u5fc3\u7406\u98a8\u96aa\u5df2\u6210\u70ba\u91cd\u8981\u7684\u516c\u5171\u885b\u751f\u8b70\u984c\u3002<\/p>\n\n\n\n<h5 class=\"wp-block-heading\">2. \u9748\u6027\u8abf\u7bc0\uff1a\u6e1b\u7de9\u5fc3\u7406\u58d3\u529b\u7684\u6f5b\u5728\u529b\u91cf<\/h5>\n\n\n\n<p class=\"wp-block-paragraph\">\u7814\u7a76\u7684\u95dc\u9375\u767c\u73fe\u5728\u65bc\uff0c<strong>\u9748\u6027\u8d8a\u9ad8\u7684\u7167\u9867\u8005\uff0c\u5176\u6182\u9b31\u75c7\u72c0\u8207\u7167\u9867\u8005\u8ca0\u64d4\u4e4b\u9593\u7684\u95dc\u806f\u986f\u8457\u8f03\u5f31<\/strong>\u3002\u4e5f\u5c31\u662f\u8aaa\uff0c<strong>\u9748\u6027\u5728\u5176\u4e2d\u767c\u63ee\u4e86\u4fdd\u8b77\u6027\u8abf\u7bc0\u4f5c\u7528<\/strong>\uff0c\u7279\u5225\u662f\u5728\u65e5\u5e38\u884c\u7a0b\u58d3\u529b\u3001\u7d93\u6fdf\u58d3\u529b\u3001\u8207\u7f3a\u4e4f\u5bb6\u5ead\u652f\u6301\u9019\u4e09\u500b\u65b9\u9762\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9019\u9ede\u4e0d\u50c5\u518d\u6b21\u80af\u5b9a\u9748\u6027\u4f5c\u70ba\u5fc3\u7406\u8abf\u9069\u8cc7\u6e90\u7684\u6f5b\u80fd\uff0c\u4e5f\u63d0\u9192\u6211\u5011\u5728\u6574\u9ad4\u7167\u8b77\u8a08\u756b\u4e2d\uff0c\u61c9\u91cd\u8996\u7167\u9867\u8005\u7684\u9748\u6027\u9700\u6c42\u8207\u4fe1\u4ef0\u80cc\u666f\uff0c\u4e0d\u61c9\u5c07\u5176\u8996\u70ba\u300c\u9644\u5c6c\u300d\u6216\u300c\u7121\u95dc\u91ab\u7642\u300d\u7684\u8981\u7d20\u3002<\/p>\n\n\n\n<h5 class=\"wp-block-heading\">3. \u5be6\u52d9\u8207\u653f\u7b56\u610f\u6db5\uff1a\u6574\u5408\u9748\u6027\u7167\u8b77\u7684\u5fc5\u8981\u6027<\/h5>\n\n\n\n<p class=\"wp-block-paragraph\">\u6839\u64da\u672c\u7814\u7a76\u7d50\u679c\uff0c\u672a\u4f86\u764c\u75c7\u7167\u8b77\u653f\u7b56\u548c\u81e8\u5e8a\u5be6\u52d9\u61c9\u8003\u616e\u4ee5\u4e0b\u5e7e\u9ede\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9748\u6027\u8a55\u4f30<\/strong>\uff1a\u5c07\u9748\u6027\u89c0\u9ede\u7d0d\u5165\u764c\u75c7\u7167\u9867\u8005\u7684\u5e38\u898f\u8a55\u4f30\u5de5\u5177\uff0c\u8b58\u5225\u9ad8\u98a8\u96aa\u7fa4\u9ad4\u3002<\/li>\n\n\n\n<li><strong>\u5c08\u696d\u57f9\u8a13<\/strong>\uff1a\u63d0\u5347\u8b77\u7406\u4eba\u54e1\u8207\u793e\u5de5\u5c0d\u9748\u6027\u654f\u611f\u5ea6\u8207\u61c9\u5c0d\u6280\u5de7\uff0c\u63a8\u52d5\u8de8\u5c08\u696d\u6574\u5408\u3002<\/li>\n\n\n\n<li><strong>\u9748\u6027\u4ecb\u5165<\/strong>\uff1a\u958b\u767c\u5982\u975c\u5fc3\u51a5\u60f3\u3001\u9748\u6027\u5718\u9ad4\u5c0d\u8a71\u3001\u5b97\u6559\u652f\u6301\u7cfb\u7d71\u9023\u7d50\u7b49\u8cc7\u6e90\uff0c\u5be6\u969b\u652f\u6301\u7167\u9867\u8005\u7684\u5167\u5728\u529b\u91cf\u3002<\/li>\n<\/ul>\n\n\n\n<h5 class=\"wp-block-heading\">4. \u672a\u4f86\u7814\u7a76\u5efa\u8b70<\/h5>\n\n\n\n<p class=\"wp-block-paragraph\">\u96d6\u7136\u6b64\u7814\u7a76\u4f7f\u7528\u7e31\u8cab\u8a2d\u8a08\u4e26\u52a0\u5165\u6df7\u5408\u7dda\u6027\u6a21\u578b\u63a7\u7ba1\u8b8a\u9805\uff0c\u4ecd\u5efa\u8b70\u5f8c\u7e8c\u80fd\u64f4\u5c55\u81f3\u66f4\u9577\u671f\u7684\u8ffd\u8e64\uff0c\u4e26\u63a2\u7d22\u4e0d\u540c\u5b97\u6559\u8207\u6587\u5316\u80cc\u666f\u4e2d\u9748\u6027\u4fdd\u8b77\u4f5c\u7528\u7684\u666e\u904d\u6027\u6216\u5dee\u7570\u6027\u3002\u540c\u6642\uff0c\u4e5f\u61c9\u63a2\u8a0e\u9748\u6027\u662f\u5426\u53ef\u900f\u904e\u8a13\u7df4\u6216\u5e72\u9810\u63d0\u5347\u5176\u8abf\u7bc0\u6548\u80fd\uff0c\u4e26\u9032\u4e00\u6b65\u5f71\u97ff\u53d7\u7167\u9867\u8005\u7684\u9810\u5f8c\u8207\u5bb6\u5ead\u7167\u9867\u54c1\u8cea\u3002<\/p>\n\n\n\n<h5 class=\"wp-block-heading\">\u7e3d\u7d50<\/h5>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u7814\u7a76\u70ba\u764c\u75c7\u7167\u8b77\u8005\u7684\u5fc3\u7406\u5065\u5eb7\u8b70\u984c\uff0c\u5e36\u4f86\u6975\u5177\u50f9\u503c\u7684\u6d1e\u898b\u2014\u2014<strong>\u9748\u6027\u4e0d\u662f\u62bd\u8c61\u4fe1\u5ff5\uff0c\u800c\u662f\u4e00\u7a2e\u5177\u9ad4\u53ef\u64cd\u4f5c\u3001\u5be6\u969b\u53ef\u5f71\u97ff\u5fc3\u7406\u7d50\u679c\u7684\u91cd\u8981\u5fc3\u7406\u8cc7\u6e90<\/strong>\u3002\u5c07\u9748\u6027\u7167\u8b77\u7d0d\u5165\u764c\u75c7\u6cbb\u7642\u9ad4\u7cfb\uff0c\u4e0d\u50c5\u6709\u52a9\u65bc\u6e1b\u8f15\u7167\u9867\u8005\u8ca0\u64d4\uff0c\u4e5f\u53ef\u80fd\u7522\u751f\u6b63\u5411\u7684\u9023\u9396\u6548\u61c9\uff0c\u6539\u5584\u6574\u9ad4\u7167\u8b77\u54c1\u8cea\u8207\u75c5\u4eba\u751f\u6d3b\u54c1\u8cea\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7de8\u8b6f\u8207\u8a55\u8ad6: <a href=\"https:\/\/pi-union.com\/zh\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u767e\u806f\u91ab\u5b78\u7de8\u8b6f<\/a><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Translator and Reviewer:\u00a0<a href=\"https:\/\/pi-union.com\/zh\/\" target=\"_blank\" rel=\"noreferrer noopener\">PI-Union Medical Science<\/a><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Source:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38131143\">https:\/\/pubmed.ncbi.nlm.nih.gov\/38131143<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u70ba\u5584\u6700\u6a02\uff0c\u8acb\u652f\u6301\u4ee5\u4e0b\u516c\u76ca\u5718\u9ad4:<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.canceraway.org.tw\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u8ca1\u5718\u6cd5\u4eba\u53f0\u7063\u764c\u75c7\u57fa\u91d1\u6703<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/ccfroc.org.tw\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u4e2d\u83ef\u6c11\u570b\u5152\u7ae5\u764c\u75c7\u57fa\u91d1\u6703<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.ecancer.org.tw\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u764c\u75c7\u5e0c\u671b\u57fa\u91d1\u6703<\/a><\/li>\n<\/ol>","protected":false},"excerpt":{"rendered":"<p>\u9748\u6027\u8abf\u7bc0\u764c\u75c7\u7167\u9867\u8005\u8ca0\u8377\u8207\u6182\u9b31\u75c7\u72c0\u4e4b\u9593\u7684\u95dc\u4fc2 La IS, Johantgen M, Storr CL, Zhu [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":25547,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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